J.
David Van Horn
Assistant
Professor of Chemistry
University
of Missouri-Kansas City
EDUCATION
Ph.D. 1999 Chemistry University of Utah, Salt Lake City, UT
B.A. 1995 Chemistry Point Loma Nazarene University, San Diego, CA
PROFESSIONAL EMPLOYMENT
2002-Present Assistant Professor, Department of Chemistry, UMKC
1999-2001 Postdoctoral Research Assistant, University of California, Berkeley and Lawrence Berkeley National Laboratory
1999 Instructor, Department of Chemistry, University of Utah
RESEARCH AREA
BioInorganic Chemistry; Metal-Peptide Complexes; Heavy Metal and Actinide Chemistry and Biochemistry; Inorganic Analytical Chemistry and Reagents
SOCIETY MEMBERSHIPS/PROFESSIONAL HONORS
1993 American Chemical Society
1996 American Association for the Advancement of Science
2002 Society for Biological Inorganic Chemistry
1993 AIURP Undergraduate Research Fellow
1995 NIH Predoctoral Trainee in Biological Chemistry
REPRESENTATIVE PUBLICATIONS
Dipesh
Ghosh, Douglas R. Powell and J. David Van Horn. “The Cr(III) tris-Malonato Anion with an Organic
Cation.” In preparation.
Huan
Huang, Shveta Chaudhary and J. David Van Horn “Actinide Biochemistry. 1.
Uranyl Interactions with DAHK and Derivatives.”
Submitted to Inorg. Chem.
J.
David Van Horn, Grzegorz Bulaj, David P. Goldenberg and Cynthia J. Burrows
“The Cys-Xaa-His Metal-Binding Motif.
{N} versus {S} Coordination and Nickel Mediated Formation of Cysteinyl
Sulfinic Acid.” J. Biol. Inorg.
Chem. 2003, 8, 601-610.
Victor L. Heasley, James D. Anderson, Zachary S. Bowman, John C. Hanley, Jr., Geoffery A. Sigmund, David Van Horn, Dale F. Shellhamer “Formation of Dimer-Type Ketals in the Reaction of 2,4,6-Trichlorophnol and 2,4,6-Trichloro-m-cresol with Calcium Hypochlorite in Methanol: Conversion to Quinones and Other Compounds” J. Org. Chem. 2002, 67, 6827-6830.
J. David Van Horn, Christine J. Gramer, Brendon O’Sullivan, Kristy M. Clarke Jurchen, Dan M. J. Doble, Kenneth N. Raymond “Iron(III) 2,3-Dihydroxyterephthalamides Revisited. Charge Effects on Highly Stable Ferric Complexes” C. R. Acad. Sci. Paris, Chimie 2002, 5, 395-404.
Marguerite Pitié, J. David Van Horn, Denis Brion, Cynthia J. Burrows, and Bernard Meunier “Targeting the DNA Cleavage Activity of Copper Phenanthroline and Clip-Phen to AT Tracts via Linkage to a Poly-N-methylpyrrole.” Bioconjugate Chem. 2000, 11, 892-900.
J. David Van Horn and Cynthia J. Burrows “Formation of trans-3-Hydroxy-4-phenylbutyrolactone from trans-Styrylacetic Acid and Aqueous KHSO5.” Tetrahedron Lett. 1999, 40, 2069-2070.
Robyn P. Hickerson, Victor Duarte, J. David Van Horn, Ronelito J. Perez, James G. Muller, Steven E. Rokita, Cynthia J. Burrows, “DNA Cleavage vs. Crosslinking using Nickel Peptides: Mechanistic Aspects.” In Metals and Genetics; Sarkar, B., Ed.; Plenum: New York, 1999.
Victor L. Heasley, Elias, D. S.; Paul E. Erdman, J. David Van Horn, Paul Whitelaw, P. M.; Shellhammer, D. F. “Effects of Pyridine on the Regio- and Stereo-chemistry in the Addition of Bromine Chloride to a,b-unsaturated Aldehydes and Ketones.” J. Chem. Soc., Perkin Trans. 2, 1996, 761-765.
INVITED PRESENTATIONS
J.
David Van Horn. Raytown High
School, Raytown, MO. October 10, 2003 “Metals in Biology:
Lead, Uranium and Chromium Analytical and Biochemical Projects”
J.
David Van Horn. American Chemical
Society, Kansas City Section, January 30, 2003, Kansas City MO. “Research and
Applications in Bio-Inorganic Chemistry”
J. D. Van Horn "Highly Stable Complexes of Iron and the Actinides in Aqueous Media." Glenn T. Seaborg Seminar Series, Lawrence Berkeley National Laboratory, CA. December 13, 2001.
J. D. Van Horn, C. J. Burrows, ACS National Meeting April 1-5.2001 San Diego CA. "Ni(II) and Cu(II) Tripeptide Complexes: Possible Mechanisms in Nickel Toxicity."
OTHER PRESENTATIONS
Poster
Shveta Chaudhary, Dipesh Ghosh, Joel Pinkston, Mohamed Rabile and J.
David Van Horn.* Midwest American
Chemical Society Meeting, November 5-7, 2003. Columbia, MO “CHROMIUM(III)
BIOMIMETIC AND BIOLOGICAL CHEMISTRY: A
BROAD APPROACH”
Huan
Huang, Mohamed Rabile, J. David Van Horn.* Midwest American Chemical Society Meeting, November 5-7,
2003. Columbia, MO “URANYL BIOMIMETIC AND BIOLOGICAL CHEMISTRY:
Uranyl-Peptide Interactions."
Kambiz
Amini,
Deendayal Dinakarpandian, David Van Horn.*
3rd Annual SEARCH Symposium, April 23, 2003.
Kansas City, MO. “A Hunt for Metal Binding Motifs in Genome Sequences.”
J. D. Van Horn, K. N. Raymond, E. Radkov. ACS National Meeting April 1-5.2001 San Diego CA. Poster 190, Inorganic Division. "Comparison of the Aqueous Actinide and Lanthanide Coordination Chemistry of Dihydroxyterephthalamide, Dihydroxybenzene sulfonamide, and Hydroxypyridinone Ligands."
C. J. Burrows, J. D. Van Horn, G. Bulaj ACS National Meeting April 1-5.2001 San Diego CA. "Nickel-mediated Cysteine Oxidation in Small Peptides."
D. Van Horn, C. Gramer, J. Xu, K. N. Raymond. Poster. Plutonium Futures--The Science. July 10-13, 2000, Santa Fe, NM. "Catechols and Hydroxypyridinones in Actinide Chemistry."
Christine Gramer, J. David Van Horn, Jide Xu, and Kenneth N. Raymond. Presented at the Environmental Management Science Program National Workshop, Atlanta, GA, April 24-28, 2000. "Catechols and Hydroxypyridinones in Actinide Separations: Bridging the Gap between Basic Chemistry and Remediation Technology."
J. David Van Horn, and Cynthia J. Burrows. Presented at the Graduate Research Seminar in Bioinorganic Chemistry Gordon Conference, January 1998; Poster "Copper and Nickel Peptide Complexes with Thiolate or Thioether Coordination: Probing the Limits of NH2-Terminal Metal Binding Motifs."
J. David Van Horn. Presented at the Department of Chemistry, University of Utah, April 1996; Graduate Student Seminar "Solid Phase Organic Chemistry: New Tools in Small Molecule Synthesis."
J. David Van Horn and Victor L. Heasley. Presented at the Southern California Conference on Undergraduate Research, California Institute of Technology, November 1993; paper CHM.I.3E.
11/2002
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